STRAIGHT FROM THE HEART – Lipids called ceramides may be better predictors of cardiovascular problems than cholesterol

Leslie, M. Science, Mar 16, 2023

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Ceramides improve cardiovascular risk prediction beyond low-density lipoprotein cholesterol

Leiherer et al. Eur. Heart J. Open (2024) 4, 1–9.

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Ceramides and Phosphatidylcholines Associate with Cardiovascular Diseases in the Elderly

Katajamäki et al. Clin Chem. 2022 Dec 6;68(12):1502-1508.

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Plasma ceramides independently predict all-cause mortality in men aged 85

Strandberg et al. Age Ageing. 2022 Jun 1;51(6)

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Prior myocardial infarction, coronary artery disease extent, diabetes mellitus, and CERT2 score for risk stratification in stable coronary artery disease

Hilvo et al. European Journal of Preventive Cardiology. Published 28 August 2021

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Comparison of recent ceramide-based coronary risk prediction scores in cardiovascular disease patients

Leiherer et al. European Journal of Preventive Cardiology. Published: 21 August 2021

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Absolute and relative risk prediction in cardiovascular primary prevention with a modified SCORE chart incorporating ceramide-phospholipid risk score and diabetes mellitus

Hilvo et al. European Heart Journal Open, Published: 13 July 2021

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Primary cardiovascular risk prediction by LDL-cholesterol in Caucasian middle-aged and older adults: a joint analysis of three cohorts

Hilvo et al. European Journal of Preventive Cardiology, Published 01 June 2021

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A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer

Salminen et al. Cancers 2021, 13(8), 1764.

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Plasma ceramide and phospholipid-based risk score and the risk of cardiovascular death in patients after acute coronary syndrome

Gencer et al. 2020 European Journal of Preventive Cardiology. Published online Dec 2020

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Ceramides improve atherosclerotic cardiovascular disease risk assessment beyond standard risk factors

Meeusen et al. 2020 Clinica Chimica Acta 511 (2020) 138–142

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Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification

Hilvo et al. 2020. Frontiers in Endocrinology. September 2020 | Volume 11 | Article 570628

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Associations between specific plasma ceramides and severity of coronary-artery stenosis assessed by coronary angiography

Mantovani et al. 2020 Diabetes & Metabolism, 46(2):150-157.

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Prediction of Residual Risk by Ceramide‐Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy

Hilvo et al. 2020 JAHA, Published Online May 2020

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Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients

Hilvo et al. 2019 Eur Heart J. Published online: 18 June 2019

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Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

Ruuth M. et al. 2018 European Heart Journal, 2018: 39 (27),2562–2573.

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Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients

Anroedh et al. 2018 The Journal of Lipid Research. June 1, 2018, doi: 10.1194/jlr.P081281

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Ceramide stearic to palmitic acid ratio predicts incident diabetes

Hilvo et al. Diabetologia (2018) 61: 1424. https://doi.org/10.1007/s00125-018-4590-6

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PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions

Hilvo et al. 2018 Atherosclerosis Volume 269, Pages 159–165

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High-grade ovarian serous carcinoma patients exhibit profound alterations in lipid metabolism

Braicu et al. Oncotarget. 2017; 8:102912-102922

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