Prediction of Residual Risk by Ceramide‐Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy

Hilvo et al. 2020 JAHA, Published Online May 2020

Read more  

Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients

Hilvo et al. 2019 Eur Heart J. Published online: 18 June 2019

Read more  

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

Ruuth M. et al. 2018 European Heart Journal, 2018: 39 (27),2562–2573.

Read more  

Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients

Anroedh et al. 2018 The Journal of Lipid Research. June 1, 2018, doi: 10.1194/jlr.P081281

Read more  

Ceramide stearic to palmitic acid ratio predicts incident diabetes

Hilvo et al. Diabetologia (2018) 61: 1424. https://doi.org/10.1007/s00125-018-4590-6

Read more  

PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions

Hilvo et al. 2018 Atherosclerosis Volume 269, Pages 159–165

Read more  

High-grade ovarian serous carcinoma patients exhibit profound alterations in lipid metabolism

Braicu et al. Oncotarget. 2017; 8:102912-102922

Read more  

Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 Cohort

Havulinna et al. Arterioscler Thromb Vasc Biol. 2016; 36

Read more  

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

Laaksonen et al. European Heart Journal, Published online: 28 April 2016

Read more  

Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas

Hilvo et al. Cancer Res. 2016 Feb 15;76(4):796-804

Read more  

Lipidomics: a tool for studies of atherosclerosis

Ekroos K et al. Curr Atheroscler Rep. 2010 Jul;12(4):273-81

Read more  

Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides

Kauhanen D et al. Anal Bioanal Chem. 2016 May;408(13):3475-83

Read more  

Lipidomics in drug discovery

Vihervaara T et al. Drug Discov Today 2014 Feb;19(2):164-70

Read more  

STOMPing forward: statins, muscle complaints and CK

Laaksonen R. Atherosclerosis. 2013 Oct;230(2):256-7

Read more  

Beyond LDL-C lowering: distinct molecular sphingolipids are good indicators of proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency

Jänis et al. Atherosclerosis 2013 Jun;228(2):380-5

Read more  

Identifying new Risk Markers and Potential Targets for Coronary Artery Disease: The Value of the Lipidome and Metabolome

Laaksonen R. Cardiovasc Drugs Ther. 2016 Feb;30(1):19-32

Read more  

Plasma concentrations of molecular lipid species in relation to coronary plaque characteristics and cardiovascular outcome: Results of the ATHEROREMO-IVUS study

Cheng JM et al. Atherosclerosis 2015 Dec;243(2):560-6.

Read more  

Molecular lipids identify cardiovascular risk and are efficiently lowered by simvastatin and PCSK9 deficiency

Tarasov K et al. J Clin Endocrinol Metab. 2014 Jan;99(1):E45-52

Read more  

Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese

Puri P et al. J Lipid Res. 2016 Mar 28

Read more  

Long-term performance and stability of molecular shotgun lipidomic analysis of human plasma samples

Heiskanen LA et al. Anal Chem. 2013 Sep 17;85(18):8757-63

Read more